Buscar
Mostrando ítems 1-10 de 33
Corneal angiogenesis modulation by cysteine cathepsins: in vitro and in vivo studies
(Elsevier B.V., 2015-05-01)
Corneal avascularization is essential for normal vision. Several antiangiogenic factors were identified in cornea such as endostatin and angiostatin. Cathepsin V, which is highly expressed in the cornea, can hydrolyze human ...
Bevacizumab for ocular neovascular diseases: a systematic review
(Associação Paulista de Medicina - APM, 2009-05-01)
CONTEXT AND OBJECTIVE: Many eye diseases involve increased local levels of vascular endothelial growth factor (VEGF), and there are several therapeutic strategies for them. Thus, the aim of this study was to evaluate the ...
Respuestas tisulares y vasculares en retinopatía hipertensiva con anticuerpos monoclonales como terapia antiangiogénica
(Universidad de La Salle. Ediciones Unisalle, 22 d)
Twelve-month safety of intravitreal injections of bevacizumab (Avastin (R)): results of the Pan-American Collaborative Retina Study Group (PACORES)
(Springer, 2008-01-01)
Background Vascular endothelial growth factor (VEGF) plays an important role in many diseases of the posterior pole that are characterized by macular edema and/or intraocular neovascularization. Recently anti-VEGF agents ...
Sistemas nanoparticulados basados en lípidos destinados al tratamiento de neovascularizaciones oculares
(2018-03-27)
El presente trabajo de Tesis Doctoral, se centró en el desarrollo de nuevas Plataformas de Liberación de Fármacos (PLFs) basadas en nanotecnología como estrategia de optimización de la farmacoterapia relacionada a patologías ...
Ácido corosólico na oftalmologia: avaliação da atividade antiangiogênica, segurança e toxicidade ocular, desenvolvimento e caracterização de implante biodegradável de liberação prolongada
(Universidade Federal de Minas GeraisUFMG, 2018-02-23)
Angiogenesis occurs in pathological conditions as an attempt to repair tissue damage through the local formation of blood vessels. However, in proliferative retinopathies, neovascularization brings effects that impair ...
In Vitro And In Vivo Anti-angiogenic Effects Of Hydroxyurea
(Academic Press Inc., 2014)
New Use of Rapamycin Stent in Non-Responding Facial Lymphatic Malformation
(Biomedical Journal of Scientific, 2019)
Introduction:
Vascular anomalies represent a diagnostic and therapeutic difficulty. A lymphatic malformation (LM) corresponds to a low-flow vascular malformation. Sclerotherapy is the preferred treatment. Recently, ...
Corneal neovascularization: a combined approach of bevacizumab and suramin showed increased antiangiogenic effect through downregulation of BFGF and P2X2
(Taylor & Francis, 2017-12)
Purpose: the objective is to analyze the antiangiogenic mechanism of suramab, a pharmaceutical compound of bevacizumab and suramin, in a rabbit model of corneal angiogenesis. Material and methods: corneal neovascularization ...